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Olus in G1. Nuclear speckles, or splicing speckles, are punctuating foci where splicing things accumulate for effective RNA processing events. When splicing speckles disassemble, its machinery remains dispersed through mitosis aggregating in mitotic inter-chromatin granules (MIGs). In early G1, when RNAPII transcription is re-activated, pre-mRNA splicing machinery starts accumulating within the nu


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