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didn't come across any optimistic role of AP-1 in the course of DMBA/TPA papilloma induction. Elk1, as a member of ETS oncogene family, is an identified target of MAPK which has been reported to play a essential function in cell proliferation. We located lowered Elk1 expression in JWAD2/D2 mouse skin tissues too as in cultured JWAD2/D2 MEFs, suggesting that Elk1 may very well be involved in TPA in

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