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60S ribosomal subunits (Figure 7C), consistent with the possibility that ribosomes contain RNAs with these terminal modifications. Alternatively, the mature 30 -end of 5S rRNA, in the context of Mdmx complexes, could be modified with 20 , 30 -cyclic phosphates (72). Rex1p, a 30 to 50 exonuclease in the RNase D family, is involved with modifying the 30 ends of both 5S and 5.8S rRNA in yeast; howeve

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